Desmoid Tumors
Desmoid tumors, also known as aggressive fibromatosis, are noncancerous growths that occur in the connective tissue. They most commonly develop in the abdomen, arms, and legs, but they can form anywhere in the body.
Characteristics and Behavior
While desmoid tumors are benign and do not spread to other parts of the body, they can be very aggressive locally. They often invade nearby structures and organs, which is why they are managed by oncologists despite not being true cancers. The behavior of these tumors can vary; some grow slowly and may not require immediate treatment, while others grow rapidly and necessitate intervention through surgery, radiation therapy, chemotherapy, or other medications.
Symptoms
The symptoms of desmoid tumors depend largely on their location. Common symptoms include:
- A noticeable mass or swelling
- Pain
- Loss of function in the affected area
- Cramping and nausea, particularly when the tumors are located in the abdomen
When to See a Doctor
It is important to consult a doctor if you experience any persistent or concerning symptoms. Early diagnosis and treatment can help manage the condition effectively.
Causes
The exact cause of desmoid tumors is not well understood. However, these tumors develop when a connective tissue cell undergoes changes in its DNA. These genetic changes prompt the cell to multiply rapidly, forming a tumor that can invade and damage healthy tissue.
Risk Factors
Several factors can increase the risk of developing desmoid tumors, including:
- Young Adult Age: Desmoid tumors are more common in younger adults, particularly those in their 20s and 30s, and are rare in children and older adults.
- Genetic Syndromes: Individuals with familial adenomatous polyposis (FAP), a genetic condition that causes numerous colon polyps, have a higher risk of desmoid tumors. FAP is inherited and caused by a gene mutation.
- Pregnancy: Occasionally, desmoid tumors may develop during or shortly after pregnancy.
- Injury: A small number of cases occur in individuals who have recently experienced an injury or undergone surgery.
For further information on desmoid tumors, you can refer to sources such as the Mayo Clinic or other medical literature.
Sources
- Mayo Clinic Staff. "Desmoid Tumor." Mayo Clinic, Mayo Clinic.
- National Organization for Rare Disorders (NORD). "Desmoid Tumor." rarediseases.org.
- American Cancer Society. "Desmoid Tumor." cancer.org.
