Table of Contents
What is zonisamide?
Zonisamide is employed in conjunction with other medications to address partial seizures in adults and adolescents aged 16 and older. It may also have applications beyond those specified in this medication guide.
Zonisamide side effects
Emergency medical assistance is necessary if signs of an allergic reaction or severe skin reaction occur. Immediate reporting to the doctor is advised for sudden mood or behavior changes, including heightened depression or anxiety, panic attacks, and impulsive thoughts. The potential serious side effects of zonisamide, such as eye issues, decreased sweating, increased seizures, skin rash, metabolic acidosis, blood cell disorders, and kidney stones, are highlighted. Common side effects are also listed.
Related/similar drugs
A list of drugs related or similar to zonisamide is presented, including gabapentin, clonazepam, lamotrigine, lorazepam, pregabalin, diazepam, and topiramate.
Warnings
Warnings associated with zonisamide usage are detailed, including the risk of permanent vision loss, severe skin reactions, decreased sweating, and increased body temperature. The section also emphasizes the potential for thoughts about suicide, necessitating vigilance for changes in mood and behavior by both patients and their caregivers.
Before taking this medicine
Conditions and circumstances that may restrict or impact zonisamide usage are outlined. These include allergies to the medication or sulfa drugs, specific health issues, and the need for pregnancy prevention due to potential harm to unborn babies. Regular monitoring and checks for mood changes are stressed.
How should I take zonisamide?
Detailed instructions on the proper administration of zonisamide, including dosage adjustments, taking with or without food, and the swallowing of capsules whole, are provided. The need for blood and kidney function tests, potential seizure increase upon sudden cessation, and proper storage procedures are also highlighted.
Zonisamide dosing information
Specific dosing information for adults aged 16 and older is presented, including initial doses, titration, maintenance doses, and maximum doses. The extended duration to achieve steady state levels, potential side effects, and the prescriber’s discretion regarding treatment duration at lower doses are emphasized.
What happens if I miss a dose?
Guidance on what to do if a dose of zonisamide is missed is provided, emphasizing the importance of not taking double doses.
What happens if I overdose?
Emergency measures for zonisamide overdose are detailed, including symptoms such as slow heart rate, lightheadedness, fainting, and shallow breathing.
What should I avoid while taking zonisamide?
Patients are advised on activities to avoid while taking zonisamide, such as driving or hazardous activities. The caution against alcohol consumption due to potential side effects is emphasized.
What other drugs will affect zonisamide?
Potential interactions between zonisamide and other drugs are discussed, with a focus on medications causing drowsiness. The importance of informing the doctor about all concurrent medications is highlighted.