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Table of Contents
What is Zegalogue?
Zegalogue is a prescribed medication designed to address severe hypoglycemia, or very low blood sugar, in individuals aged 6 years and older who have diabetes. Its efficacy and safety in children under 6 years old are not established.
- Who should not use Zegalogue?
Avoid Zegalogue if you have a tumor known as pheochromocytoma in the adrenal gland atop your kidneys or an insulinoma tumor in your pancreas.
Before using Zegalogue
Prior to Zegalogue use, inform your healthcare provider of your medical conditions, including pancreatic tumors, allergies to dasiglucagon or any Zegalogue components, prolonged fasting, adrenal insufficiency, chronic hypoglycemia, pregnancy, or breastfeeding. Disclose all medications, including prescriptions, over-the-counter drugs, vitamins, and herbal supplements.
Related/similar drugs
Similar medications include glucagon, Baqsimi, diazoxide, Gvoke, GlucaGen, and Proglycem.
How should I use Zegalogue?
Adhere to your healthcare provider’s instructions and carefully read the accompanying Instructions For Use. Educate your caregiver on Zegalogue storage and administration before an emergency arises. Act promptly in emergencies, and once safe, consume fast-acting (e.g., fruit juice) and long-acting (e.g., crackers with cheese or peanut butter) sources of sugar. Keep your healthcare provider informed of Zegalogue use.
Zegalogue side effects
Zegalogue may lead to high blood pressure, low blood sugar, or serious allergic reactions. Common side effects include nausea, vomiting, headache, diarrhea, and injection site pain.
How should I store Zegalogue?
Store Zegalogue in a refrigerator (36°F to 46°F/2°C to 8°C) and avoid freezing. It can also be stored at room temperature (68°F to 77°F/20°C to 25°C) for up to 12 months. Replace Zegalogue before the expiration date on the red protective case.
General information about the safe use of Zegalogue
Use Zegalogue solely for its intended purpose, as outlined in the Patient Information leaflet. Do not administer Zegalogue for conditions not prescribed, and keep it out of reach of others. Refer to healthcare professionals for information tailored to them.
What are the ingredients in Zegalogue?
Active ingredient: dasiglucagon (dasiglucagon hydrochloride)
Inactive ingredients: tromethamine, sodium chloride, and water for injection. Hydrochloric acid and/or sodium hydroxide may be added to adjust pH.
INSTRUCTIONS FOR USE
Zegalogue is employed for treating severe hypoglycemia where assistance is required. It contains a single dose of dasiglucagon in a prefilled autoinjector or prefilled syringe and cannot be reused. Familiarize yourself with these instructions before emergencies, share them with family and friends, and store Zegalogue appropriately.
How to throw away (dispose of) Zegalogue
Dispose of used autoinjectors or syringes in an FDA-cleared sharps disposal container, adhering to community guidelines. Ensure the container is made of heavy-duty plastic, leak-resistant, and properly labeled for hazardous waste. Follow state or local laws regarding disposal, and do not recycle used sharps disposal containers. For more details on safe sharps disposal, consult the FDA’s website.